Synonyms
CMD1D; CMH2; CMPD2
Description
Troponin T is one of three troponin isoforms found in the tropomyosin-troponin complex. This complex is responsible for the calcium sensitivity of the contractile apparatus in the muscle. Cardiac Troponin T is used as a biological marker for cardiomyocytes and its level in serum is frequently used as an indicator of myocardial cell injury.
Molecular Weight
Approximately 35.8 kDa.
AA sequence
SDIEEVVEEY EEEEQEEAAV EEEEDWREDE DEQEEAAEED AEAEAETEET RAEEDEEEEE AKEAEDGPME ESKPKPRSFM PNLVPPKIPD GERVDFDDIH RKRMEKDLNE LQALIEAHFE NRKKEEEELV SLKDRIERRR AERAEQQRIR NEREKERQNR LAEERARREE EENRRKAEDE ARKKKALSNM MHFGGYIQKQ AQTERKSGKR QTEREKKKKI LAERRKVLAI DHLNEDQLRE KAKELWQSIY NLEAEKFDLQ EKFKQQKYEI NVLRNRINDN QKVSKTRGKA KVTGRWK
Appearance
Sterile colorless liquid.
Purity
> 98 % by SDS-PAGE and HPLC analyses.
Endotoxin
< 1.0 EU per 1μg of the protein by the LAL method.
Formulation
Supplied as a 0.2 μm filtered solution in 10 mM Tris-HCl, pH8.0, 250 mM NaCl, with 50% glycerol.