Synonyms
Combretastatin A-4
Combrestatin A4
(Z)-2-METHOXY-5-(3,4,5-TRIMETHOXYSTYRYL)PHENOL
Description
Combretastatin A-4 is an inhibitor of microtubule polymerization derived from the South African willow bush which causes mitotic arrest and selectively targets and reduces or destroys existing blood vessels, causing decreased tumor blood supply.
Molecular Formula
C18H20O5
SMILES
COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2)OC)OC)OC)O
Melting Point
84.5-85.5ºC
Applications
Antineoplastic Agents, Phytogenic