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Cat Number: API19608298

Clascoterone

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CAS Number

19608-29-8

Synonyms

CB-03-01
Cortexolone 17alpha-propionate
17 alpha-propionate

Description

Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. It binds to androgen receptors with high affinity. By competing with androgens for binding to androgen receptors, clascoterone works by blocking the androgen receptor signalling cascades that promote acne pathogenesis, such as sebaceous gland proliferation, excess sebum production, and inflammatory pathways.

Molecular Weight

402.5

Molecular Formula

C24H34O5

SMILES

CCC(=O)OC1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)C(=O)CO

EINECS

685-282-9

Appearance

White powder

Boiling Point

538.9±50.0 ℃ | Condition: Press: 760 Torr