Cat Number: API364782343

Cinacalcet HCL

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CAS Number

364782-34-3

Synonyms

Cinacalcet hydrochloride
Sensipar
Mimpara

Description

Cinacalcet increases the sensitivity of calcium-sensing receptors on chief cells in the parathyroid gland to extracellular calcium, thereby reducing parathyroid hormone (PTH) secretion. A reduction in PTH levels inhibits osteoclast activity, which may result in a decrease in cortical bone turnover and bone fibrosis, and normalization of serum calcium and phosphorus levels.

Molecular Weight

393.9

Molecular Formula

C22H23ClF3N

SMILES

CC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl

EINECS

620-490-5

Melting Point

175-177℃ (dec.)

Standard

In-house