Description
5,7-Dichloro-8-hydroxy-2-methylquinoline is an anti-infective agent.
MolecularFormula
C10H7Cl2NO
Solubility
Soluble in DMSO (46 mg/ml at 25℃), water
Storage
Store at room temperature
MeltingPoint
108-112℃ (lit.)(dec.)
IC50
Vacuolar aminopeptidase 1: EC5050 = 5.39 µM (Saccharomyces cerevisiae S288c); Botulinum neurotoxin type A: IC50 = 10.1 µM (Clostridium botulinum); 60S ribosomal protein L19-A: EC5050 = 14.7 µM (Saccharomyces cerevisiae S288c); Vero: IC50 >25 µM (Chlorocebus aethiops)
pKValue
pKa: 2.47, pKb: 7.51
Specification
Anti-infective drugs
PreparationUse
Chlorquinaldol-promestriene vaginal tablets (200 mg)
Standard
National Drug Standard YBH12062006-2014Z