Chewable Tablets

Fig.1 Chewable Tablets

Chewable tablets are a popular and patient-friendly form of oral medication that offers convenience and ease of administration. Chewable tablets are formulated using a combination of active pharmaceutical ingredients, sweeteners, flavors, and excipients. The formulation has been carefully designed to provide a pleasant flavor and chewable texture while maintaining the stability and efficacy of the drug.

Protheragen-ING offers comprehensive chewable tablet development services and is committed to developing chewable tablet formulations that meet the highest standards of quality, efficacy, and, taste. With our expertise in formulation, manufacturing, and customization, we can create customized formulations that precisely meet your specifications, whether you need a specific active ingredient or a combination of ingredients.

Advantages of Chewable Tablets

Types of Chewable Tablets

Protheragen-ING specializes in developing different types of chewable tablets including:

The General Preparation Process for Chewable Tablets

(1) Formulation Development

We select the active pharmaceutical ingredient and other excipients such as sweeteners, flavoring agents, and binders to achieve the desired taste, texture, and stability.

(2) Granulation or Tabletting

We granulate or directly press formulation mixtures into tablets. Granulation is often used to improve flow and compressibility.

(3) Tablet Compression

We use tablet presses to compact granulated or formulated mixtures into chewable tablets. Chewable tablets are designed to have a soft, chewable texture.

(4) Coating (optional)

In some cases, chewable tablets may need to be coated to provide additional protection, improve stability, or enhance appearance. The coatings we provide are usually made from food-grade materials.

(5) Quality Control

We conduct rigorous quality control testing to ensure chewable tablet integrity, uniformity, and performance. This includes tests for weight variation, hardness, disintegration, dissolution, and stability.

Our Technology

We use advanced technologies to optimize formulations to ensure excellent stability, bioavailability, and homogeneity.

Odor Masking Technology Granulation Technology
  • Wet granulation coating
  • Solid Dispersions
  • Microencapsulation
  • Ion exchange
  • Spray coagulation and spraying
  • Adsorbent formulation technology (solvent method)
  • Non-aqueous granulation / dry granulation
  • Aqueous phase granulation / wet granulation
  • Direct compression

Fig.2 Schematic representation of dry granulation, wet granulation and direct compression.Fig. 1 Schematic representation of dry granulation, wet granulation and direct compression. (Rodríguez-Pombo L, et al. 2022)

Contact us today to discuss your chewable tablet development project and discover how we can help you bring your innovative products to market successfully.

Reference

  1. Rodríguez-Pombo L, et al. (2022). "Innovations in Chewable Formulations: The Novelty and Applications of 3D Printing in Drug Product Design." Pharmaceutics, 14(8), 1732.

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