Cat Number: API26973240

Ceftezole Sodium

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CAS Number

26973-24-0

Synonyms

Ceftezol
Ceftezolum
Ceftezole [INN]

Description

Ceftezole is a semisynthetic first-generation cephalosporin with antibacterial activity. Ceftezole binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Molecular Weight

440.5

Molecular Formula

C13H12N8O4S3

SMILES

C1C(=C(N2C(S1)C(C2=O)NC(=O)CN3C=NN=N3)C(=O)O)CSC4=NN=CS4

Appearance

Powder

Density, g/cm3

2.09

Melting Point

155 ℃ (dec.)