Cat Number: API84957299

Cefpirome Sulfate

Inquiry

CAS Number

84957-29-9

Synonyms

Cefpiroma
Cefpiromum
Cefrom

Description

Cefpirome is a semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefpirome binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Molecular Weight

514.6

Molecular Formula

C22H22N6O5S2

SMILES

CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4=CC=CC5=C4CCC5)C(=O)[O-]

Appearance

White Solid

Melting Point

150℃(dec.)

Standard

EP/USP/JP