Cat Number: API183133962

Cabazitaxel

APIs
CAS Number
183133-96-2
Description
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.
Molecular Weight
835.932
Molecular Formula
C45H57NO14
Solubility
Soluble in DMSO (100 mg/ml), and ethanol (50 mg/ml).
Storage
Store at -20℃
SMILES
CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC
Appearance
Crystalline
pKa
11.2
Boiling Point
870.7±65.0 ℃ at 760 mmHg
Density, g/cm3
1.3±0.1
Melting Point
180 ℃
Refractive Index
1.592
Flash Point
480.4±34.3 ℃
Vapour Pressure
0.0±0.3 mmHg at 25℃
Standard
In-house
Facility GMP
Qualification
USMF/CDE/DMF/FDA/EMA
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