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Cat Number: PIPB-0392

Bz-rA

CAS Number

4546-55-8

Synonyms

N6-Benzoyladenosine, N6-benzoyl-adenosine;
N-Benzoyladenosine;
N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; Benzamide, N-(9-beta-D-ribofuranosyl-9H-purin-6-yl)

Description

N6-Benzoyladenosine is a purine nucleoside that is synthesized from uridine and has a high resistance to phosphorylation. It is found in the mitochondrial matrix of rat hepatocytes and can be used as a specific agent for the treatment of symptoms related to Parkinson's disease. N6-Benzoyladenosine inhibits protein synthesis by inhibiting the catalytic subunit of guanine nucleotide-binding proteins, which are involved in cellular energy production. It also inhibits camp levels and camp concentrations in mitochondria, which may be due to its effects on the trimethylbenzodiazepine receptor.

Molecular Weight

371.35

Molecular Formula

C17H17N5O5

EINECS

610-251-3

SMILES

C1=CC=C(C=C1)C(=O)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O

Appearance

solid

Color

White to off-white