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Cat Number: PIPE-0532

Bruceantin

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CAS Number

41451-75-6

Synonyms

Bruceantine
NSC 165563
NSC-165563

Description

Bruceantin is a triterpene quassinoid antineoplastic antibiotic isolated from the plant Brucea antidysenterica. Bruceantin inhibits the peptidyl transferase elongation reaction, resulting in decreased protein and DNA synthesis. Bruceantin also has antiamoebic and antimalarial activity. (NCI04)

Molecular Weight

548.6

Molecular Formula

C28H36O11

SMILES

CC1=C(C(=O)CC2(C1CC3C45C2C(C(C(C4C(C(=O)O3)OC(=O)C=C(C)C(C)C)(OC5)C(=O)OC)O)O)C)O

Appearance

Powder

Storage

Room temperature

Purity

HPLC≥95% 96% 97%