Cat Number: API59803984

Brimonidine

CAS Number

59803-98-4

Description

Brimonidine is a full α2-adrenergic receptor (α2-AR) agonist.

MolecularWeight

292.14

MolecularFormula

C11H10BrN5

SMILEs

C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br

Solubility

Soluble in ethanol

Storage

Store at room temperature

MeltingPoint

235-236℃

BoilingPoint

~432.55℃ at 760 mmHg

Density

~1.8 g/cm³

RefractiveIndex

1.8

OpticalActivity

α2-AR: IC50 = 3 nM (human); α2-AR: IC50 = 3.6 nM (rat); α2A-AR: IC50 = 298 nM (human); α2B-AR: IC50 = 1.05 µM (human); α1D-AR: IC50 = 1.72 µM (human)

pKValue

pKb: 7.69

FlashPoint

215.4±31.5 ℃

VapourPressure

0.0±1.0 mmHg at 25℃

Specification

an alpha-2 adrenergic agonist used to treat glaucoma and ocular hypertension, as well as facial erythema in rosacea.

PreparationUse

Ophthalmic drops

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

INFORMATION

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