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Cat Number: 92054ES

BMP-7

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Genus

Human

Source

E.coli

Synonyms

BMP7, BMP-7, bone morphogenetic protein 7, Eptotermin alfa, OP-1,

Description

BMP-7 is a member of the TGF-β superfamily which is supposed to be one of the most potent anabolic factors of chondrocytes. The growth factor domain of human BMP-7 shares 98% aa sequence identity with mouse and rat BMP-7.

Molecular Weight

The protein has a predicted 13.1 kDa.

Purity

> 95% as determined by SDS-PAGE.

Biological Activity

Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.
The expected ED50 for this effect is 20-40 ng/ml.

Endotoxin

< 1 0EU /mg of the protein by the LAL method.

Formulation

Lyophilized from a 0.22 μm filtered solution containing 0.085% TFA, 30% ACN,5% mannitol.

Reconstitution

Centrifuge the tube before opening. It is recommended to redissolve in 4 mM HCl.

Note

10, 50μg

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