Source
E.coli(His-tagged)
Synonyms
BDNF, ANON2, BULN2, Abrineurin
Description
BDNF, short for Brain-Derived Neurotrophic Factor, is a protein that a crucial role in the growth, development, and survival of neurons in the brain. It is primarily produced in the hippocampus, cortex, and basal forebrain regions of the brain. BDNF is a vital protein in the brain that supports neuronal growth, survival, and synaptic plasticity.
Molecular Weight
The protein has a predicted MW of 13.51 kDa. The protein migrates to 15-19 kDa based on Tris-Bis PAGE result.
Purity
> 95% as determined by SDS-PAGE.
Endotoxin
Less than 1EU per μg by the LAL method.
Formulation
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.