Cat Number: API81732469

Bambuterol Hydrochloride

CAS Number

81732-46-9

Description

Bambuterol Hcl is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.IC50 value:Target: beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.

MolecularWeight

403.901

MolecularFormula

C18H30ClN3O5

SMILEs

Cl.CN(C)C(=O)OC1=CC(=CC(OC(=O)N(C)C)=C1)C(O)CNC(C)(C)C

Solubility

Soluble in water (~33 mg/ml), DMSO, and methanol.

Storage

Store at -20℃

MeltingPoint

222-224ºC

BoilingPoint

500.9ºC at 760 mmHg

Density

1.154g/cm³

RefractiveIndex

1.533

IC50

CYP2D6: IC50 = 2 µM (human)

FlashPoint

256.7ºC

PreparationUse

beta adrenergic agonist, bronchodilator, cholinesterase inhibitor

QualitySpecification

EP/CP

Standard

EP/CP

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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