Cat Number: API677007748

Avatrombopag Meleate

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CAS Number

677007-74-8

Synonyms

E5501 MALEATE UNII-GDW7M2P1IS GDW7M2P1IS

Description

Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia.

Molecular Weight

765.7

Molecular Formula

C33H38Cl2N6O7S2

SMILES

C1CCC(CC1)N2CCN(CC2)C3=C(N=C(S3)NC(=O)C4=CC(=C(N=C4)N5CCC(CC5)C(=O)O)Cl)C6=CC(=CS6)Cl.C(=CC(=O)O)C(=O)O

EINECS

973-683-4

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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