Description
L-Arginine Monohydrochloride is a precursor of nitric oxide synthesis that induces vasodilation in vivo. Nitric oxide potentiates insulin-mediated glucose uptake through the increase in blood flow.
MolecularFormula
C6H15ClN4O2
SMILEs
C(C[C@@H](C(=O)O)N)CN=C(N)N.Cl
Appearance
Crystalline powder
Solubility
Soluble in water (211 mg/ml at 20℃), and hot alcohol (slightly).
MeltingPoint
226-230 ℃(lit.)
BoilingPoint
409.1ºC at 760 mmHg
OpticalActivity
α20D +22.0±0.5, c = 5 in 5 M HCl; α20D +22.5±0.5, c = 8 in HCl(1+1)
PreparationUse
amino acid drug. After taking it, it can participate in the ornithine cycle and promote the conversion of blood ammonia into non-toxic urea through the ornithine cycle, thus reducing blood ammonia. However, if the liver function is defient, the enzyme activity of urea formation in the liver decreases, so the blood ammonia-lowering effect of arginine is not very satisfactory. It is suitable for patients with hepatic coma who are not suitable for the input of sodium ions.