Cat Number: API170729803

Aprepitant

Inquiry

CAS Number

170729-80-3

Description

Aprepitant is a selective neurokinin-1 (NK-1) receptor antagonist.

Molecular Weight

534.43

Molecular Formula

C23H21F7N4O3

Storage

Store at -20℃

SMILES

C[C@@H](O[C@H]1OCCN(CC2=NNC(=O)N2)[C@H]1C1=CC=C(F)C=C1)C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F

Density, g/cm3

1.5±0.1

Melting Point

242-250℃

Refractive Index

1.564

Standard

USP/CP/JP
Facility GMP

Preparation Use

An antiemetic chemical compound that belongs to “substance P” antagonists (SPA) with its effect being blocking the neurokinin 1(Nk1) receptor, used for the prevention of acute and delayedchemotherapy-induced nausea and vomiting(CINV) and for prevention ofpostoperative nausea and vomiting.

Qualification

USMF/ASMF/JPMF/DMF/CEP/CDE

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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