Apremilast is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM.
MolecularWeight
460.5
MolecularFormula
C22H24N2O7S
Storage
Store at 4℃
MeltingPoint
152-156℃
BoilingPoint
741.3±60.0 ℃ at 760 mmHg
Density
1.4±0.1 g/cm3
RefractiveIndex
1.612
FlashPoint
402.1±32.9 ℃
VapourPressure
0.0±2.5 mmHg at 25℃
PreparationUse
an oral phosphodiesterase 4 inhibitor used in the treatment of adults with active psoriatic arthritis and adults with moderate to severe plaque psoriasis.