Cat Number: API520365

Apigenin

CAS Number

520-36-5

Description

Apigenin is an antioxidant plant flavanoid which contains anti-inflammatory and anticancer properties. Apigenin may induce apoptosis and may inhibit proliferation of tumor cells by arresting the cell cycle at the G2/M phase. Apigenin is also known to be a MAP kinase inhibitor and a selective inhibitor of Protein Kinase 2 (CK2).

MolecularWeight

270.24

MolecularFormula

C15H10O5

SMILEs

C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O

Appearance

Powder

Solubility

Soluble in DMSO (27 mg/mL), 1M KOH (50 mg/mL), water (Immiscible), alcohol, and Ethanol

Storage

Store at -20℃

MeltingPoint

>300℃ (lit.)

BoilingPoint

~555.5℃ at 760 mmHg

Density

~1.5 g/cm³

RefractiveIndex

1.73

IC50

TPA: IC50 = 59.44 µ M (human breast cancer cells); TPA: IC50 = 31.15 µ M (human breast cancer cells); ATP: IC50 = 10 ± 0.5 µ M (protein kinase C); yrosine kinases fibroblast growth factor receptor: IC50 = 20 µ M (protein kinase C); pp60v-src: IC50 = >200 µ M (protein kinase C)

FlashPoint

217.1±23.6 ℃

VapourPressure

0.0±1.6 mmHg at 25℃

PreparationUse

antioxidant, has the effect of lowering blood pressure and relaxing blood vessels, preventing atherosclerosis, and inhibiting tumors.

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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