Description
Ancitabine hydrochloride is an antineoplastic agent.
MolecularFormula
C9H11N3O4•HCl
Solubility
Soluble in water.
OpticalActivity
α20/D -21.8°, c = 2 in water
IC50
B-cell specific antigen receptor-induced NF-kB activation: IC50 = 640 nM (Jurkat cells ); Streptokinase A: EC5050 = 4.89 µM (Streptococcus pyogenes serotype M1); Cytotoxic to Streptococcus: EC5050 = 53.11 µM; B-cell specific antigen receptor-induced NF-kB activation: IC50 = >80 µM (HEK-293T cell line)
Specification
Antitumor drugs
PreparationUse
Ancitabine for injection (0.1 g)
Standard
National Drug Standard WS-10001-(HD-1450)-2003