Description
1-Adamantylamine is a building block for an L-piperidinamide catalyst used in an enantioselective Strecker reaction of phosphinoyl imines.
SMILEs
C1C2CC3CC1CC(C2)(C3)N
Solubility
Soluble in 1 N HCI (50 mg/ml), and hot methanol. Insoluble in water.
MeltingPoint
206-208℃ (lit.)
BoilingPoint
225.7±8.0 ℃ at 760 mmHg
IC50
H3N2 subtype: IC50 = 630 nM; Influenza A virus: IC50 = 1.25 µM; Influenza A virus (H5N1): IC50 = 3.84 µM
pKValue
pKa: 10.45 (Predicted), pKb: 10.76 (Predicted)
VapourPressure
0.1±0.4 mmHg at 25℃