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Cat Number: API315300

Allopurinol

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CAS Number

315-30-0

Synonyms

1H-Pyrazolo[3,4-d]pyrimidin-4-ol
Zyloprim
Lopurin

Description

Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints. This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals. Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout. It was initially approved by the FDA in 1966 and is now formulated by several manufacturers.

Molecular Weight

136.11

Molecular Formula

C5H4N4O

SMILES

C1=NNC2=C1C(=O)NC=N2

EINECS

206-250-9

Appearance

odorless tasteless white microcrystalline powder

pKa

10.2 (at 25℃)