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Cat Number: API138112762

Agomelatine

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CAS Number

138112-76-2

Synonyms

Thymanax
Valdoxan
N-(2-(7-Methoxynaphthalen-1-yl)ethyl)acetamide

Description

Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively.

Molecular Weight

243.3

Molecular Formula

C15H17NO2

SMILES

CC(=O)NCCC1=CC=CC2=C1C=C(C=C2)OC

EINECS

629-727-7

Appearance

White Solid

Melting Point

106-108℃