Cat Number: API142340996

Adefovir Dipivoxil

APIs
CAS Number
142340-99-6
Description
Adefovir dipivoxil is an antiviral acyclic nucleoside phosphonate (ANP) analog.
MolecularWeight
501.47
MolecularFormula
C20H32N5O8P
Appearance
Powder
Solubility
Soluble in ethanol (100 mg/ml at 25℃), DMSO (100 mg/ml at 25℃), water
Storage
Store at -20℃
MeltingPoint
100℃
BoilingPoint
~641.0℃ at 760 mmHg
Density
~1.4 g/cm3
RefractiveIndex
1.57
IC50
CEM-SS: EC5050 = 40 nM (human); Hepatitis B virus: IC50 = 330 nM; Vero: IC50 = 0.6 µM (grivet); Vaccinia virus: IC50 = 5.1 µM; Cowpox virus: IC50 = 13 µM
pKValue
pKb: 4.16
PreparationUse
for chronic hepatitis B
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