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Cat Number: API142340996

Adefovir Dipivoxil

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CAS Number

142340-99-6

Description

Adefovir dipivoxil is an antiviral acyclic nucleoside phosphonate (ANP) analog.

MolecularWeight

501.47

MolecularFormula

C20H32N5O8P

Appearance

Powder

Solubility

Soluble in ethanol (100 mg/ml at 25℃), DMSO (100 mg/ml at 25℃), water

Storage

Store at -20℃

MeltingPoint

100℃

BoilingPoint

~641.0℃ at 760 mmHg

Density

~1.4 g/cm³

RefractiveIndex

1.57

IC50

CEM-SS: EC5050 = 40 nM (human); Hepatitis B virus: IC50 = 330 nM; Vero: IC50 = 0.6 µM (grivet); Vaccinia virus: IC50 = 5.1 µM; Cowpox virus: IC50 = 13 µM

pKValue

pKb: 4.16

PreparationUse

for chronic hepatitis B

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