Description
Adefovir dipivoxil is an antiviral acyclic nucleoside phosphonate (ANP) analog.
MolecularFormula
C20H32N5O8P
Solubility
Soluble in ethanol (100 mg/ml at 25℃), DMSO (100 mg/ml at 25℃), water
BoilingPoint
~641.0℃ at 760 mmHg
IC50
CEM-SS: EC5050 = 40 nM (human); Hepatitis B virus: IC50 = 330 nM; Vero: IC50 = 0.6 µM (grivet); Vaccinia virus: IC50 = 5.1 µM; Cowpox virus: IC50 = 13 µM
PreparationUse
for chronic hepatitis B