Synonyms
2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene];ethyl 2-chloro-2-[(4-methoxyphenyl)hydrazinylidene]acetate;Apixaban Impurity B;(Z)-Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate(Apixaban);Apixaban-2;1-(4-methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxamide;Chloro[(4-methoxyphenyl)hydrazono]acetic acid ethyl ester;Ethyl chloro[(4-methoxyphenyl)hydrazono]acetate
Description
Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester is an ester derivative and can be used as an intermediate in the synthesis of apixaban.
Molecular Formula
C11H13ClN2O3
InChI
ATNPZEGMKLGIFA-UHFFFAOYSA-N
InChIKey
ATNPZEGMKLGIFA-UHFFFAOYSA-N
SMILES
C(OCC)(=O)C(Cl)=NNC1=CC=C(OC)C=C1
Color
Yellow to Dark Yellow
pKa
11.63±0.10(Predicted)
Boiling Point
349.0±44.0 ℃(Predicted)
Applications
Apixabani ntermediate