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Cat Number: API103902

Acetaminophen

CAS Number

103-90-2

Description

Acetaminophen (paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic drug.

MolecularWeight

151.163

MolecularFormula

C8H9NO2

SMILEs

CC(=O)NC1=CC=C(C=C1)O

Solubility

Soluble in water (14 g/l at 20℃), ethanol (100 mM), DMSO (100 mM), methanol (50 mg/ml), and DMF.

Storage

Store at room temperature

MeltingPoint

168-172 ℃(lit.)

BoilingPoint

387.8±25.0 ℃ at 760 mmHg

Density

1.3±0.1 g/cm³

RefractiveIndex

1.619

IC50

Arachidonate 15-lipoxygenase: IC50 = 28.38 µM (Oryctolagus cuniculus); FLAP: IC50 = 44 µM (human); COX-3: IC50 = 460 µM (dog); COX-1: IC50 = >1000 µM (mouse); COX-2: IC50 = >1000 µM

pKValue

pKa: 9.86, pKb: 1.72

FlashPoint

188.4±23.2 ℃

VapourPressure

0.0±0.9 mmHg at 25℃

Specification

an analgesic and antipyretic compound, an analgesic and fever-reducing agent. Acetaminophen is designed for moderate analgesia

PreparationUse

tablets

HOURS

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Sunday : 9.30 AM–1.00 PM
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