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Cat Number: PIPE-0747

7-Ethyl-10-hydroxycamptothecin

Inquiry

CAS Number

86639-52-3

Synonyms

7-Ethyl-10-hydroxycamptothecin
SN 38
SN 38 lactone

Description

7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer. SN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative Breast Cancer, among others.

Molecular Weight

392.4

Molecular Formula

C22H20N2O5

EINECS

643-093-9

SMILES

CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)O

Appearance

Pale Yellow to Light Yellow Solid

Storage

Room temperature