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Cat Number: INT35654569

4-Chloro-6,7-dimethoxyquinoline

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APIs
CAS Number
35654-56-9
Synonyms
6,7-DIMETHOXY-4-CHLOROQUINOLINE;4-CHLORO-6,7-DIMETHOXYQUINOLINE;4-Chloro-6,7-dimethoxyquioline;Quinoline, 4-chloro-6,7-dimethoxy-;4-CHLORO-6,7-DIMETHOXYQUINOLINE(35654-56-9);Cabozantinib 4-Chloroquinoline Impurity;4-Chloro-6,7-dimethoxyquinoline >oro-6,7-dimethoxyquinoL
Description
4-Chloro-6,7-dimethoxyquinoline can be used as an intermediate for the synthesis of various pharmaceutical and biologically active compounds. It is used for the preparation of Tivozanib (T447205), and Cabozantinib (C051500), acting as anticancer agents.
Molecular Weight
223.66
Molecular Formula
C11H10ClNO2
EINECS
676-028-8
InChI
WRVHQEYBCDPZEU-UHFFFAOYSA-N
InChIKey
WRVHQEYBCDPZEU-UHFFFAOYSA-N
SMILES
N1C2C(=CC(OC)=C(OC)C=2)C(Cl)=CC=1
Appearance
Solid
Color
Pale Brown to Light Brown
Storage
Keep in dark place, sealed in dry, room temperature
pKa
3.95±0.30(Predicted)
Boiling Point
325.2±37.0 ℃(Predicted)
Density, g/cm3
1.265±0.06(Predicted)
Melting Point
132.0 to 136.0 ℃
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