Cat Number: INT284462379

4-(4-Aminophenoxy)-N-methylpicolinamide

CAS Number

284462-37-9

Synonyms

4-(4-Aminophenoxy)-N-methylpyridine-2-carboxamide
4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide
[4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide

Description

[4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide is an intermediate of Sorafenib, which is a kinase inhibitor drug used for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma.

Molecular Weight

243.26

Molecular Formula

C13H13N3O2

EINECS

608-211-5

SMILES

CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)N

Appearance

Light brown to brown solid

Boiling Point

476.8±40.0℃ (Predicted)