Cat Number: INT273206921

3-Azabicyclo[3.1.0]hexane-3-carboxylicacid,6-amino-,1,1-dimethylethylester

APIs
CAS Number
273206-92-1
Synonyms
tert-Butyl rel-(1R,5S,6S)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate;(1α,5α,6α)-6-AMino-3-azabicyclo[3.1.0]hexane-3-carboxylic Acid 1,1-DiMethylethyl Ester;exo-6-Amino-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester;3-Azabicyclo[3.1.0]hexane-3-carboxylic acid, 6-amino-, 1,1-dimethylethyl ester, (1alpha,5alpha,6alpha)-;rac(1R,5S,6S)-tert-butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate;tert-butyl (1S,5R)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate;tert-butyl (exo-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate;trans-tert-butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
Description
3-Azabicyclo[3.1.0]hexane-3-carboxylicacid,6-amino-,1,1-dimethylethylester is an intermediate in the preparation of a novel series of Histone Deacetylase (HDAC) Inhibitors, demonstrating class I selectivity and good oral bioavailability. It can also be used in the synthesis of Alatrofloxacin Mesylate (A511400).
Molecular Weight
198.27
Molecular Formula
C10H18N2O2
Storage
Under inert gas (nitrogen or Argon) at 2–8 ℃
pKa
8.52±0.20(Predicted)
Boiling Point
275℃
Density, g/cm3
1.144
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