Cat Number: PIPB-0227

2'-OMe-ibu-G Phosphoramidite

CAS Number

150780-67-9

Synonyms

N-blocked-5'-O-DMT-2'-O-Me CED guanosine phosphoramidite;5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;5'-O-DMT-2'-O-Me-rG(N-iBu)-3'-CEDPA;2'-OMe-ibu-G Phosphoramidite;5'-O-DMT-2'-O-Me-G(ibu) phosporamidite;DMT-2′O-Methyl-rG(ib) Phosphoramidite;ibu-2'-OMe-G Phosphoramidite

Description

2'-OMe-ibu-G Phosphoramidite is used in the synthesis of native-like crosslinked duplex RNA via interstrand crosslinking reaction between vinylpurine on one strand and target cytosine or uracil on the opposite strand.

Molecular Weight

869.94

Molecular Formula

C45H56N7O9P

EINECS

2017-001-1

InChI

IRRDHRZUOZNWDJ-MLLDKZSOSA-N

InChIKey

IRRDHRZUOZNWDJ-MLLDKZSOSA-N

SMILES

O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,44,47,r|

Appearance

powder

Color

white to off-white

Storage

Inert atmosphere,2-8℃

Purity

≥98%

pKa

9.16±0.20(Predicted)

Melting Point

138 - 140℃