Cat Number: PIPB-0275

2'-O-4'-C-Locked-T CE Phosphoramidite

APIs
CAS Number
206055-75-6
Synonyms
3-[[(1R,3R,4R,7S)-1-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
DMTr-LNA-5MeU-3-CED-phosphoramidite
(1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
Description
DMTr-LNA-5MeU-3-CED-phosphoramidite is vital for Locked Nucleic Acid (LNA) oligonucleotide synthesis, which features a ribonucleoside connected by a methylene unit between 2'-oxygen and 4'-carbon atoms, mirroring DNA polymerization in structure and process.
Molecular Weight
772.8
Molecular Formula
C41H49N4O9P
EINECS
686-262-2
SMILES
CC1=CN(C(=O)NC1=O)C2C3C(C(O2)(CO3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N
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