Cat Number: API68962

17α-Hydroxyprogesterone

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CAS Number

68-96-2

Description

17a-Hydroxyprogesterone is an antiestrogen compound.

MolecularWeight

330.461

MolecularFormula

C21H30O3

SMILEs

CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O

Appearance

Crystalline

Solubility

Soluble in water (partly), chloroform, methanol, and Dichloromethane.

Storage

Store at -20℃

MeltingPoint

276℃

BoilingPoint

482.9±45.0 ℃ at 760 mmHg

Density

1.2±0.1 g/cm³

RefractiveIndex

1.56

OpticalActivity

α20D +92.1, c = 1.0 in chloroform; α20D +90±5, c = 1 in chloroform

IC50

Progesterone receptor: IC50 = 12 nM (bovine); GR: IC50 = 51 nM (human); Androgen Receptor: IC50 = 739 nM (rat); ERK 1: IC50 = 3.16 µM (human); Plasmodium falciparum W2: IC50 = 3.16 µM

pKValue

pKa: 13.03

FlashPoint

260.0±25.2 ℃

VapourPressure

0.0±2.8 mmHg at 25℃

PreparationUse

a metabolite of Progesterone, used prophylactically for the 12th to 37th week of pregnancy, particularly in women who are in the high-risk category for premature delivery-anticoagulant

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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