Cat Number: PIVA-0086

β-Nicotinamide mononucleotide

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CAS Number

1094-61-7

IUPAC Name

3-Carbamoyl-1-(5-O-phosphono-β-D-ribofuranosyl)pyridin-1-ium

MDL Number

MFCD00038748

EC Number

214-136-5

Synonym

β-NMN, β-Nicotinamide ribose monophosphate, NMN, Nicotinamide ribotide, Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate

MolecularWeight

334.22

MolecularFormula

C11H15N2O8P

SMILES

C[C@H]1[C@@H](C)[C@@H](O[C@@H]1COP(O)([O-])=O)[n+]2cccc(c2)C(N)=O

InChI

1S/C13H19N2O6P/c1-8-9(2)13(21-11(8)7-20-22(17,18)19)15-5-3-4-10(6-15)12(14)16/h3-6,8-9,11,13H,7H2,1-2H3,(H3-,14,16,17,18,19)/t8-,9+,11+,13+/m0/s1

InChI key

YYNOOWWEYJELSF-SEMCEJNYSA-N

Appearance

White to light yellow powder

Description

β-NMN is an intermediate in the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed biosynthesis of nicotinamide adenine dinucleotide (NAD+). NAMPT mediates the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to produce β-NMN. β-NMN adenyltransferase subsequently converts β-NMN to NAD+.

Purity

≥95% (HPLC)
≥95% (spectrophotometric assay)

Melting Point

166 °C(dec.)

Solubility

Soluble in water
Insoluble in acetone
Soluble in PBS (10 mg/ml).

Storage

−20°C

Application

β-Nicotinamide mononucleotide (NMN) is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.

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Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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